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KMID : 0191120160310050817
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Journal of Korean Medical Science
2016 Volume.31 No. 5 p.817 ~ p.821
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The First Successful Heart-Lung Transplant in a Korean Child with Humidifier Disinfectant-Associated Interstitial Lung Disease
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Jhang Won-Kyoung
Park Seong-Jong
Lee Eun
Yang Song-I
Hong Soo-Jong
Seo Ju-Hee
Kim Hyung-Young
Park Jeong-Jun
Yun Tae-Jin
Kim Hyeong-Ryul
Kim Yong-Hee
Kim Dong-Kwan
Park Seung-Il
Lee Sang-Oh
Hong Sang-Bum
Shim Tae-Sun
Choi In-Cheol
Yu Jin-Ho
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Abstract
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From 2006 to 2011, an outbreak of a particular type of childhood interstitial lung disease occurred in Korea. The condition was intractable and progressed to severe respiratory failure, with a high mortality rate. Moreover, in several familial cases, the disease affected young women and children simultaneously. Epidemiologic, animal, and post-interventional studies identified the cause as inhalation of humidifier disinfectants. Here, we report a 4-year-old girl who suffered from severe progressive respiratory failure. She could survive by 100 days of extracorporeal membrane oxygenation support and finally, underwent heart-lung transplantation. This is the first successful pediatric heart-lung transplantation carried out in Korea.
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KEYWORD
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Heart-Lung Transplantation, Extracorporeal Membrane Oxygenation, Interstitial Lung Disease, Inhalation Exposure
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